Direct observation of dynamic protein interactions involving human microtubules using solid-state NMR spectroscopy
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چکیده
منابع مشابه
Intermolecular Interactions and Protein Dynamics by Solid‐State NMR Spectroscopy
Understanding the dynamics of interacting proteins is a crucial step toward describing many biophysical processes. Here we investigate the backbone dynamics for protein GB1 in two different assemblies: crystalline GB1 and the precipitated GB1-antibody complex with a molecular weight of more than 300 kDa. We perform these measurements on samples containing as little as eight nanomoles of GB1. Fr...
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ژورنال
عنوان ژورنال: Nature Communications
سال: 2020
ISSN: 2041-1723
DOI: 10.1038/s41467-019-13876-x